Prospective validation of the prognostic and predictive impact of uPA/PAI-1 in early breast cancer
This prospective analysis confirms the uPA/PAI-1 status as an independent prognostic factor and suggests a predictive impact considering benefit from chemotherapy.
Authors
- Christoph Thomssen (ORCID: https://orcid.org/0000-0002-9324-2396)
- Martina Vetter (ORCID: https://orcid.org/0000-0002-6642-9585)
- Jutta John
- Tilmann Lantzsch
- Christoph Uleer (ORCID: https://orcid.org/0000-0002-7937-8182)
- Sandy Kaufhold
- Susanne Peschel
- Edith Weigert
- Marleen Pöhler
- Marcus Bauer (ORCID: https://orcid.org/0000-0002-0657-6831)
- Kerstin Eichstädt
- Eva Johanna Kantelhardt (ORCID: https://orcid.org/0000-0001-7935-719X)
- Volker Hanf
- Vanessa Wieder
- Julia Engel (ORCID: https://orcid.org/0000-0001-6416-6876)
- Jörg Buchmann
- Karl‐Friedrich Bürrig
Institutions
- University of Hildesheim (DE)
- Universität Ulm (DE)
- Herzog August Library (DE)
- Krankenhaus St. Elisabeth und St. Barbara (DE)
- St. Bernward Krankenhaus (DE)
- Klinikum Fürth (DE)
- Martha-Maria Hospital (DE)
- Orthopädische Praxis (DE)
- University Hospital Ulm (DE)
- Asklepios (DE)
- Technische Hochschule Ulm (DE)
- Martin Luther University Halle-Wittenberg (DE)
Publication Details
- Journal
- Breast Cancer Research and Treatment
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1007/s10549-025-07850-z
- Primary Topic
- Protease and Inhibitor Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bundesministerium für Bildung und Forschung