The Role of Selenium as an Antioxidant in the Treatment of Renal Cell Carcinoma

the effects of selenium as an antioxidant in promoting cell viability in renal cell carcinoma have been controversial. In some aspects, it reduced ROS production, which increased cancer cell viability. While in another setting, selenium increased ROS levels, which correlated with more cell death. Therefore, further research needs to be conducted to prove the true effects of selenium on cancer cells.

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Publication Details

Journal
Cureus
Published
2025-12-08
DOI
https://doi.org/10.7759/cureus.98696
Primary Topic
Selenium in Biological Systems
Type
article
Field-Weighted Citation Impact
0.00
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article

The Role of Selenium as an Antioxidant in the Treatment of Renal Cell Carcinoma

Anu Vinod Ranade, Mina Taher, Ibrahim Elsharkawi, Ziad El Menawy et al.
Cureus
Selenium in Biological Systems
article

The Role of Selenium as an Antioxidant in the Treatment of Renal Cell Carcinoma

Anu Vinod Ranade, Mina Taher, Ibrahim Elsharkawi, Ziad El Menawy, Hussein Hmoud, Taqwa Atef
article en

Abstract

the effects of selenium as an antioxidant in promoting cell viability in renal cell carcinoma have been controversial. In some aspects, it reduced ROS production, which increased cancer cell viability. While in another setting, selenium increased ROS levels, which correlated with more cell death. Therefore, further research needs to be conducted to prove the true effects of selenium on cancer cells.

CureusVol. 17(12)
William Harvey Hospital (GB), University Hospital of Wales (GB), Al Jalila Foundation (AE), Manchester Royal Infirmary (GB), East Kent Hospitals University NHS Foundation Trust (GB), University of Sharjah (AE), Zayed Military Hospital (AE), Royal Manchester Children's Hospital (GB), Zayed University (AE)
Openalex Percentile: Top 54%
Selenium in Biological Systems
DOIOpen Access PDFOpenAlex
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The Role of Selenium as an Antioxidant in the Treatment of Renal Cell Carcinoma — Anu Vinod Ranade, Mina Taher, et al. · Cureus (2025) | TGRS Research Map | TGRS