Catalyst‐Controlled Cascade Annulation of CF ₃ ‐Imidoyl Sulfoxonium Ylides with Activated Nitriles for the Divergent Synthesis of Trifluoromethyl‐Substituted Pyrroles and Quinolines

A copper catalyst‐controlled cascade annulation of CF 3 ‐imidoyl sulfoxonium ylides with activated nitriles has been disclosed, which enables the divergent synthesis of trifluoromethyl‐substituted pyrroles and quinolines. For the synthesis of pyrroles, the [3 + 2] annulation proceeds to give the multisubstituted pyrrole products. For the synthesis of quinolines, the CuI‐induced intramolecular cyclization is involved in the reaction with the cleavage of CCN bond.