Blood ctDNA-specific markers predict the risk of peritoneal metastasis for advanced gastric cancer
Early postoperative persistent ctDNA positivity (especially TP53 mutation) combined with Lauren diffuse-type classification and serosal invasion can effectively identify patients at high risk of peritoneal metastasis. This integrated model provides a new strategy for precise postoperative surveillance and intervention in advanced gastric cancer.
Authors
- Ping Jiang (ORCID: https://orcid.org/0000-0002-7890-6713)
- Jun Shi (ORCID: https://orcid.org/0000-0002-2547-171X)
- Ying Mu (ORCID: https://orcid.org/0000-0002-7084-1791)
- Fuyuan Xing
- Weihong Sun (ORCID: https://orcid.org/0000-0002-2422-7440)
- Chun‐Wei Peng
Institutions
- Qingdao University (CN)
- Anhui Medical University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1007/s12672-025-04198-0
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00