The effectiveness of bisphosphonates vs denosumab in people with dementia or frailty post hip fracture: a multi-database cohort study
Bisphosphonate users had higher rates of subsequent fracture than denosumab users. Mortality rates in men were lower with bisphosphonates than denosumab. There were no significant differences by dementia and frailty status.
Authors
- Ching‐Lung Cheung (ORCID: https://orcid.org/0000-0002-6233-9144)
- George S. Q. Tan (ORCID: https://orcid.org/0000-0003-2526-729X)
- Chor‐Wing Sing (ORCID: https://orcid.org/0000-0002-2180-3676)
- Miyuki Hsing‐Chun Hsieh (ORCID: https://orcid.org/0000-0002-7995-7408)
- Tiantian Ma (ORCID: https://orcid.org/0000-0003-1361-4055)
- Jenni Ilomäki (ORCID: https://orcid.org/0000-0002-0348-9441)
- Edward Chia‐Cheng Lai (ORCID: https://orcid.org/0000-0002-5852-7652)
- Ian D. Cameron (ORCID: https://orcid.org/0000-0003-0147-047X)
- Miriam T Y Leung (ORCID: https://orcid.org/0000-0002-4259-7058)
- S Kim (ORCID: https://orcid.org/0000-0001-5052-1195)
- J. Simon Bell (ORCID: https://orcid.org/0000-0002-6115-2767)
- Wallis C. Y. Lau (ORCID: https://orcid.org/0000-0003-2320-0470)
- Ian Chi Kei Wong (ORCID: https://orcid.org/0000-0001-8242-0014)
- Stephen J. Wood (ORCID: https://orcid.org/0000-0002-9256-2216)
Institutions
- The University of Sydney (AU)
- Aston University (GB)
- University College London (GB)
- Monash University (AU)
- University of Hong Kong (HK)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Osteoporosis International
- Published
- 2025-12-07
- DOI
- https://doi.org/10.1007/s00198-025-07676-x
- Primary Topic
- Hip and Femur Fractures
- Type
- article
- Field-Weighted Citation Impact
- 0.00