Single-cell transcriptional profiling reveals developmental dynamics of longissimus dorsi muscle in adult and Juvenile bactrian camels
This study, for the first time, constructed a single-cell atlas and intercellular communication network of the Bactrian camel longissimus dorsi muscle, uncovered the key regulatory mechanisms governing its skeletal muscle development, and identified functionally important regulatory targets such as PCDH7. These findings not only provide a theoretical basis for the precise improvement of camel meat quality but also laid the groundwork for in-depth investigations into the adaptive evolutionary mechanisms of camel skeletal muscle.
Authors
- Fang Wan (ORCID: https://orcid.org/0000-0002-1378-8541)
- Shenyuan Wang
- Li Lu (ORCID: https://orcid.org/0000-0003-0977-6414)
- Chaolu Hasi
- Hai Long (ORCID: https://orcid.org/0000-0001-6135-1486)
- Jie Gong (ORCID: https://orcid.org/0000-0002-3923-2488)
- Junwei Cao (ORCID: https://orcid.org/0000-0002-6913-2509)
- Wenlong Wang (ORCID: https://orcid.org/0000-0003-1669-613X)
- Huanmin Zhou (ORCID: https://orcid.org/0000-0003-3852-0071)
- Ting Jia (ORCID: https://orcid.org/0000-0003-1185-6624)
- Yuting Chen (ORCID: https://orcid.org/0000-0002-0595-5717)
- Tao Li (ORCID: https://orcid.org/0000-0002-2203-3941)
- Wenguang Zhang (ORCID: https://orcid.org/0000-0002-3508-588X)
- Chunxia Liu (ORCID: https://orcid.org/0000-0002-7687-5917)
- Xin Wen (ORCID: https://orcid.org/0000-0001-6513-8623)
- Yingchun Liu (ORCID: https://orcid.org/0000-0001-7719-3355)
- Fanhua Meng (ORCID: https://orcid.org/0009-0005-3229-8651)
- Yuwen Liu (ORCID: https://orcid.org/0000-0002-2173-659X)
- Yiyi Liu (ORCID: https://orcid.org/0000-0002-2188-6336)
- Hong‐Mei Xiao (ORCID: https://orcid.org/0000-0003-1732-3554)
- Qian Song (ORCID: https://orcid.org/0000-0001-9816-932X)
- B. De
- Hongmei Bao (ORCID: https://orcid.org/0009-0008-5428-2863)
- Yanru Zhang (ORCID: https://orcid.org/0009-0009-0450-2001)
- A. Naer
Institutions
- Inner Mongolia Agricultural University (CN)
- Inner Mongolia University (CN)
- Agricultural Genomics Institute at Shenzhen (CN)
- Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences (CN)
- National Animal Husbandry Service (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3389/fphys.2025.1697432
- Primary Topic
- Animal Diversity and Health Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00