Nature’s Cardioprotective Sweetness: A Review of Dates as Functional Food in Hypertension

Dates contain numerous beneficial nutrients and bioactive compounds, including potassium, magnesium, dietary fiber, polyphenols, flavonoids, and essential fatty acids, which contribute to their antihypertensive effects. Mechanistically, these bioactives reduce oxidative stress, lower inflammation, enhance endothelial function through increased nitric oxide bioavailability, and modulate the renin-angiotensin system. Clinical studies demonstrate that regular, moderate consumption of dates can reduce systolic and diastolic blood pressure, improve lipid profiles, and positively regulate inflammatory and oxidative biomarkers without adverse metabolic or glycemic outcomes. Despite promising findings, variability in date cultivars, ripening stages, and limited standardized human trials necessitate further research. Larger, randomized clinical studies across diverse demographics are recommended to establish optimal dosage, confirm mechanisms of action, and assess long-term safety and effectiveness. This review investigates the potential of dates (<i>Phoenix dactylifera</i>) as a functional food for controlling blood pressure and protecting cardiovascular health in hypertensive individuals.

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Journal
Foods
Published
2025-12-08
DOI
https://doi.org/10.3390/foods14244208
Primary Topic
Date Palm Research Studies
Type
article
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article

Nature’s Cardioprotective Sweetness: A Review of Dates as Functional Food in Hypertension

Achmad Wildan, Fahrul Nurkolis, Antonello Santini, Edmond L. Jim et al.
Foods
Date Palm Research Studies
article

Nature’s Cardioprotective Sweetness: A Review of Dates as Functional Food in Hypertension

Achmad Wildan, Fahrul Nurkolis, Antonello Santini, Edmond L. Jim, Edwin Leopold Jim
article en

Abstract

Dates contain numerous beneficial nutrients and bioactive compounds, including potassium, magnesium, dietary fiber, polyphenols, flavonoids, and essential fatty acids, which contribute to their antihypertensive effects. Mechanistically, these bioactives reduce oxidative stress, lower inflammation, enhance endothelial function through increased nitric oxide bioavailability, and modulate the renin-angiotensin system. Clinical studies demonstrate that regular, moderate consumption of dates can reduce systolic and diastolic blood pressure, improve lipid profiles, and positively regulate inflammatory and oxidative biomarkers without adverse metabolic or glycemic outcomes. Despite promising findings, variability in date cultivars, ripening stages, and limited standardized human trials necessitate further research. Larger, randomized clinical studies across diverse demographics are recommended to establish optimal dosage, confirm mechanisms of action, and assess long-term safety and effectiveness. This review investigates the potential of dates (<i>Phoenix dactylifera</i>) as a functional food for controlling blood pressure and protecting cardiovascular health in hypertensive individuals.

FoodsVol. 14(24)
Tarumanagara University (ID), Sunan Kalijaga State Islamic University Yogyakarta (ID), Universitas Airlangga (ID), Jenderal Soedirman University (ID), Federico II University Hospital (IT), Sam Ratulangi University (ID), University of Naples Federico II (IT)
Openalex Percentile: Top 72%
Date Palm Research Studies
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