Performance of established test methods for diagnosing chronic periprosthetic joint infections caused by low-virulence pathogens
Synovial fluid %PMN and WBC, and permanent histological sections demonstrated the highest diagnostic performance for diagnosing PJI caused by low-virulence pathogens. Intraoperative frozen sections proved to be a valuable intraoperative tool, particularly in cases with unclear preoperative diagnosis. A lower cut-off for SF-%PMN may be considered to more accurately diagnose these infections.
Authors
- Reinhard Windhager (ORCID: https://orcid.org/0000-0002-6321-1804)
- Kevin Staats (ORCID: https://orcid.org/0000-0002-3459-5773)
- Irene Katharina Sigmund (ORCID: https://orcid.org/0000-0002-5068-2738)
- Markus Rupp (ORCID: https://orcid.org/0000-0001-7221-3783)
- Martin A. McNally (ORCID: https://orcid.org/0000-0003-2003-9044)
- Christoph Böhler (ORCID: https://orcid.org/0000-0002-8676-1913)
- Markus Luger (ORCID: https://orcid.org/0009-0003-6542-8948)
- Lukas Rabitsch (ORCID: https://orcid.org/0009-0001-7409-6979)
Institutions
- Universitätsklinikum Gießen und Marburg (DE)
- Nuffield Orthopaedic Centre (GB)
- University of Oxford (GB)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Bone and Joint Research
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1302/2046-3758.1412.bjr-2025-0236.r1
- Citations
- 1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Universität Wien
- Medizinische Universität Wien