The correlation between serum ECM1 and cardiac fibrosis in heart failure patients

Circulating ECM1 and LRP1 levels are elevated in chronic HF and are closely associated with cardiac dysfunction and fibrosis. These findings suggest that ECM1 and LRP1 could serve as novel biomarkers for myocardial remodeling, with potential utility in the risk stratification and monitoring of patients with HF.

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Publication Details

Journal
BMC Cardiovascular Disorders
Published
2025-12-08
DOI
https://doi.org/10.1186/s12872-025-05414-z
Primary Topic
Inflammation biomarkers and pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

The correlation between serum ECM1 and cardiac fibrosis in heart failure patients

Yuhua Xu, Han Zhongyuan, Qi Lu
BMC Cardiovascular Disorders
Inflammation biomarkers and pathways
article

The correlation between serum ECM1 and cardiac fibrosis in heart failure patients

Yuhua Xu, Han Zhongyuan, Qi Lu
article en

Abstract

Circulating ECM1 and LRP1 levels are elevated in chronic HF and are closely associated with cardiac dysfunction and fibrosis. These findings suggest that ECM1 and LRP1 could serve as novel biomarkers for myocardial remodeling, with potential utility in the risk stratification and monitoring of patients with HF.

BMC Cardiovascular DisordersVol. 26(1)
Nantong University (CN)
Openalex Percentile: Top 55%
Inflammation biomarkers and pathways
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The correlation between serum ECM1 and cardiac fibrosis in heart failure patients — Yuhua Xu, Han Zhongyuan, et al. · BMC Cardiovascular Disorders (2025) | TGRS Research Map | TGRS