Precision medicine in Moyamoya vasculopathy
Systematic integration of genotypic and multiomic profiling with hemodynamic assessment could enhance prognostic precision, optimize surgical timing, and guide antiplatelet selection in Moyamoya. Next step priorities include studying ethnically diverse multicenter registries and rigorous trials evaluating targeted and regenerative therapeutic strategies. Digital subtraction angiography (DSA)-guided diagnosis and individualized revascularization strategies remain the clinical standard.
Authors
- Yusuf Kamran Qadeer (ORCID: https://orcid.org/0000-0002-4678-1266)
- Muhammad Zeeshan Memon (ORCID: https://orcid.org/0000-0003-0207-1999)
- Jason P. Mendoza (ORCID: https://orcid.org/0000-0003-2526-5542)
- Ritik Patel
- Jonathan A. Tangsrivimol (ORCID: https://orcid.org/0000-0003-0142-3569)
- Chayakrit Krittanawong (ORCID: https://orcid.org/0009-0000-6895-8459)
Institutions
- Barrow Neurological Institute (US)
- St. Joseph's Hospital and Medical Center (US)
- Wayne State University (US)
- Henry Ford Hospital (US)
- Chulabhorn Hospital (TH)
- University of Delaware (US)
Publication Details
- Journal
- Current Opinion in Neurology
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1097/wco.0000000000001454
- Primary Topic
- Moyamoya disease diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00