The Cambridge Centre for Myelin Repair trial Two (CCMR Two): a trial protocol for a phase 2a, randomised, double-blind, placebo-controlled clinical trial of the ability of the combination of metformin and clemastine to promote remyelination in people

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Publication Details

Journal
Trials
Published
2025-12-08
DOI
https://doi.org/10.1186/s13063-025-09254-2
Citations
1
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
1.47

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article

The Cambridge Centre for Myelin Repair trial Two (CCMR Two): a trial protocol for a phase 2a, randomised, double-blind, placebo-controlled clinical trial of the ability of the combination of metformin and clemastine to promote remyelination in people

J William L Brown, Emma Cutting, Nick Cunniffe, Alasdair Coles et al.
1 citations
Trials
Multiple Sclerosis Research Studies
1.47
article

The Cambridge Centre for Myelin Repair trial Two (CCMR Two): a trial protocol for a phase 2a, randomised, double-blind, placebo-controlled clinical trial of the ability of the combination of metformin and clemastine to promote remyelination in people

J William L Brown, Emma Cutting, Nick Cunniffe, Alasdair Coles, Benson S. Chen, Trisha Mukherjee, Gioia Riboni-Verri, Christopher E McMurran, Jonathon Holland, Cyrus Daruwalla, Declan Chard, David MacManus, Wendi Qian, Rabin Gautam
article en
1 citations

Abstract

No abstract available for this paper.
TrialsVol. 26(1)
University College London Hospitals NHS Foundation Trust (GB), Queen Mary University of London (GB), University of Cambridge (GB), National Institute for Health and Care Research (GB), MRC Clinical Trials Unit at UCL (GB), National Hospital for Neurology and Neurosurgery (GB), University College London (GB)
National Institute for Health and Care Research, Department of Health and Social Care, Multiple Sclerosis Society, Cornell Center for Materials Research, NIHR Cambridge Biomedical Research Centre
Openalex Percentile: Top 13%
Multiple Sclerosis Research Studies
1.47
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The Cambridge Centre for Myelin Repair trial Two (CCMR Two): a trial protocol for a phase 2a, randomised, double-blind, placebo-controlled clinical trial of the ability of the combination of metformin and clemastine to promote remyelination in people — J William L Brown, Emma Cutting, et al. · Trials (2025) | TGRS Research Map | TGRS