Inhibition of NOX4 attenuates muscle damage and mitochondrial dysfunction in inflammatory myopathy
We showed that NOX4 is associated with muscle damage in IIM and suggest that its inhibition may have novel therapeutic effect for mitigating muscle damage and disease progression in IIM.
Authors
- Hae Rim Kang
- Seon Uk Kim
- Hyuksool Kwon (ORCID: https://orcid.org/0000-0002-0960-0198)
- Shurong Ban (ORCID: https://orcid.org/0000-0001-9782-4310)
- Eun Young Lee (ORCID: https://orcid.org/0000-0001-6718-6952)
- Jeong Yeon Kim (ORCID: https://orcid.org/0000-0001-7743-231X)
- Min-Gang Kim
- Jae Hyun Moon
Institutions
- Daejeon University (KR)
- Seoul National University (KR)
- Cancer Research Institute (US)
- New Generation University College (ET)
- Seoul National University Hospital (KR)
- National University College (PR)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1186/s13075-025-03705-6
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00