Sex-related presentation, outcome, and treatment in CICU: the SPOTlight STUDY
• This study provides a comprehensive evaluation of sex-related differences in a contemporary cohort of patients admitted to the Cardiac Intensive Care Unit (CICU), highlighting distinct admission patterns and management disparities. • Women with cardiovascular disease tend to be older at presentation, exhibit different risk factor profiles, and show distinct clinical manifestations compared to men. • It identifies higher mortality rates for women with STEMI and pulmonary embolism, emphasizing the need for improved recognition and tailored management of sex-specific differences in acute cardiovascular care.
Authors
- Tommaso Sanna (ORCID: https://orcid.org/0000-0002-5760-6885)
- Lorenzo Genuardi (ORCID: https://orcid.org/0000-0002-1641-6559)
- Gaetano Pinnacchio (ORCID: https://orcid.org/0000-0001-6642-1682)
- Simone Filomia
- Marco Giuseppe Del Buono (ORCID: https://orcid.org/0000-0002-7483-6164)
- Jacopo Lenkowicz (ORCID: https://orcid.org/0000-0002-8366-1474)
- Alessia d’Aiello (ORCID: https://orcid.org/0000-0003-3501-8684)
- Giovanna Liuzzo (ORCID: https://orcid.org/0000-0002-5714-0907)
- Daniela Pedicino (ORCID: https://orcid.org/0000-0002-4218-3066)
- Carlo Trani (ORCID: https://orcid.org/0000-0001-9777-013X)
- Laura Antenucci
- Gianluigi Saponara
- Rocco Antonio Montone (ORCID: https://orcid.org/0000-0002-6439-1018)
- M Brecciaroli
- Francesco Burzotta (ORCID: https://orcid.org/0000-0002-6569-9401)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Agostino Gemelli University Polyclinic (IT)
- University of the Sacred Heart (JP)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Clinical Research in Cardiology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1007/s00392-025-02816-z
- Primary Topic
- Acute Myocardial Infarction Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università Cattolica del Sacro Cuore