SHMT1, an amino acid metabolism-related gene, is an independent prognostic biomarker in laryngeal squamous cell carcinoma
This study presents a validated prognostic risk score model comprising AAMRGs in LSCC. Furthermore, our findings highlight the downregulation of SHMT1 in LSCC and its significant association with patient prognosis and tumor stage.
Authors
- Chunguang Shan (ORCID: https://orcid.org/0000-0002-9760-5772)
- Lin Di
- Jianxing Wang (ORCID: https://orcid.org/0000-0002-1851-9463)
- Xiangjian Zhang (ORCID: https://orcid.org/0000-0003-0114-1668)
- Qiaojing Jia
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- Hebei Science and Technology Department (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1186/s12885-025-15170-0
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hebei Province
- Horizon 2020 Framework Programme