<i>Aggregatibacter actinomycetocomitans</i> prosthetic valve endocarditis causing sequential transient ischaemic attack, rheumatoid factor-positive inflammatory polyarthritis and intracerebral haemorrhage

Subacute bacterial endocarditis is often associated with non-specific symptoms and multi-system embolic phenomena that can make diagnosis difficult. We present a case of <i>Aggregatibacter actinomycetocomitans</i> (<i>Aa</i>) prosthetic valve endocarditis, initially causing a transient ischaemic attack, inflammatory arthropathy, then intracerebral haemorrhage, the latter leading to diagnosis. <i>Aa</i> should be suspected in prosthetic valve recipients with sequential onset of inflammatory arthropathy and cerebrovascular disease.

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Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-266111
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
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article

Aggregatibacter actinomycetocomitans prosthetic valve endocarditis causing sequential transient ischaemic attack, rheumatoid factor-positive inflammatory polyarthritis and intracerebral haemorrhage

Timothy John Kleinig, Jackson Harvey, Joshua Mahadevan, Laurence Preen
BMJ Case Reports
Infective Endocarditis Diagnosis and Management
article

Aggregatibacter actinomycetocomitans prosthetic valve endocarditis causing sequential transient ischaemic attack, rheumatoid factor-positive inflammatory polyarthritis and intracerebral haemorrhage

Timothy John Kleinig, Jackson Harvey, Joshua Mahadevan, Laurence Preen
article en

Abstract

Subacute bacterial endocarditis is often associated with non-specific symptoms and multi-system embolic phenomena that can make diagnosis difficult. We present a case of <i>Aggregatibacter actinomycetocomitans</i> (<i>Aa</i>) prosthetic valve endocarditis, initially causing a transient ischaemic attack, inflammatory arthropathy, then intracerebral haemorrhage, the latter leading to diagnosis. <i>Aa</i> should be suspected in prosthetic valve recipients with sequential onset of inflammatory arthropathy and cerebrovascular disease.

BMJ Case ReportsVol. 18(12)
Royal Adelaide Hospital (AU)
Openalex Percentile: Top 50%
Infective Endocarditis Diagnosis and Management
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