Minimizing Chemoradiation Using a Surgical Algorithm for HPV‐Associated Cancer of Unknown Primary
A primary surgical approach to HPV-associated CUP of the head and neck should be considered in every patient with CUP. When combined with a robust frozen section pathology protocol helping to guide intraoperative decision-making and margin revision, and a multidisciplinary approach to adjuvant therapy, precise tumor localization can help appropriately direct adjuvant therapy.
Authors
- Brian Boyce (ORCID: https://orcid.org/0000-0003-2155-3782)
- Azeem Kaka (ORCID: https://orcid.org/0000-0002-4528-4460)
- Andre J. Burnham (ORCID: https://orcid.org/0000-0003-2541-5088)
- Mihir R. Patel (ORCID: https://orcid.org/0000-0001-6477-9728)
- Nikhil Vettikattu (ORCID: https://orcid.org/0009-0009-3685-399X)
- Mark W. El‐Deiry (ORCID: https://orcid.org/0000-0003-2355-472X)
- William A. Stokes (ORCID: https://orcid.org/0000-0002-1616-7046)
- Jennifer H. Gross (ORCID: https://orcid.org/0000-0002-4241-4821)
- Nabil F. Saba (ORCID: https://orcid.org/0000-0003-4972-1477)
- H. Michael Baddour (ORCID: https://orcid.org/0000-0001-6330-1458)
- Nicole C. Schmitt (ORCID: https://orcid.org/0000-0002-0571-3531)
- James E. Bates (ORCID: https://orcid.org/0000-0001-7060-7156)
- Kelly R. Magliocca (ORCID: https://orcid.org/0000-0002-3520-9694)
- Georges Daoud (ORCID: https://orcid.org/0000-0003-3354-957X)
- Conor Steuer (ORCID: https://orcid.org/0000-0001-6528-6319)
Institutions
- Emory University (US)
- Piedmont Cancer Institute (US)
Publication Details
- Journal
- Head & Neck
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1002/hed.70124
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00