First-Line Treatment with Tivozanib for Metastatic Renal Cell Carcinoma in Real-World Settings Across Germany: Results of the Prospective, Non-Interventional, Post-Approval Study T-Rex
These data demonstrate that first-line treatment with tivozanib was associated with clinical activity, favorable tolerability, and stable QoL in patients with mRCC treated in everyday clinical practice across Germany, including those with advanced age.
Authors
- Viktor Grünwald (ORCID: https://orcid.org/0000-0003-2083-7687)
- Claus Fieseler
- Christian Doehn
- Carsten Lange (ORCID: https://orcid.org/0000-0003-4915-0870)
- Philipp Ivanyi (ORCID: https://orcid.org/0000-0002-2862-7302)
- Silke Schirrmacher-Memmel
- Andreas Janitzky
- Norbert Marschner (ORCID: https://orcid.org/0000-0002-6098-1301)
- Horst Brenneis
- Eva Hellmis (ORCID: https://orcid.org/0000-0002-7780-8759)
- S. Seseke (ORCID: https://orcid.org/0000-0002-7700-9623)
- Diana Standhaft
- B Loehr
- Steffen Baumann
- O. Rau
- Carsten Ziske
- Andrea Distelrath
- Martin Bögemann (ORCID: https://orcid.org/0000-0002-2569-4446)
- Karen Rußwurm
- Michael Seidel (ORCID: https://orcid.org/0000-0003-3307-6370)
- Ralf Eckert
- Miriam Hegemann
- Martin Herold
Institutions
- American Urological Association (US)
- ZF Friedrichshafen (Germany) (DE)
- University Medical Center Freiburg (DE)
- Steinbeis Foundation (DE)
- Medizinische Hochschule Hannover (DE)
- Städtisches Klinikum Dessau (DE)
- Halle Zoo (DE)
- Klinikum Aschaffenburg (DE)
- University Hospital Münster (DE)
- Recordati (Ireland) (IE)
- Essen University Hospital (DE)
- University Hospital Leipzig (DE)
- Prüf- und Forschungsinstitut Pirmasens (Germany) (DE)
- University Hospital Magdeburg (DE)
- BG Klinikum Duisburg (DE)
- Klinikum Sindelfingen-Böblingen (DE)
- Institut für Automatisierung und Informatik (DE)
- University Hospital in Halle (DE)
- St. Bonifatius Hospital (DE)
- Aschaffenburg University of Applied Sciences (DE)
- Rehazentrum Wilhelmshaven (DE)
- Atos Medical (DE)
- Klinikum Wilhelmshaven (DE)
- Leipzig University (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Cancers
- Published
- 2025-12-07
- DOI
- https://doi.org/10.3390/cancers17243910
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00