Catalpol Alleviates HFpEF via Inhibition of the S100A8-RAGE-NOX4 Inflammatory Axis in Murine Hearts
CAT exerts cardioprotective effects against HFpEF by suppressing myocardial inflammation and fibrosis through modulation of the S100A8/RAGE/NOX4 signaling axis and its downstream effectors.
Authors
- Yu Cao (ORCID: https://orcid.org/0000-0002-2009-4556)
- Shuangya Li (ORCID: https://orcid.org/0009-0004-6181-3475)
- Yan Shen (ORCID: https://orcid.org/0000-0002-5870-361X)
- Yi Zhang (ORCID: https://orcid.org/0000-0001-8693-3554)
- Menghua He
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Yueyang Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/jir.s552741
- Primary Topic
- S100 Proteins and Annexins
- Type
- article
- Field-Weighted Citation Impact
- 0.00