Low burden of clinically relevant anaemia and thrombocytopenia among adolescents living with HIV receiving tenofovir/lamivudine plus dolutegravir: the CIPHER-ADOLA study in Cameroon
In the TLD era, anaemia remains common but generally mild, and thrombocytopenia is uncommon. Cytopenias were associated with unsuppressed viral load, with a stronger association for anaemia in females. These findings support programmatic targeted haemovigilance prioritising adolescents with unsuppressed viral load, particularly females, in settings where access to FBC testing is limited.
Authors
- Junie Flore Yimga
- Daniele Armenia (ORCID: https://orcid.org/0000-0002-3406-7014)
- Grâce Beloumou (ORCID: https://orcid.org/0000-0002-6870-7366)
- Nadine Fainguem (ORCID: https://orcid.org/0000-0002-8497-7948)
- Anne Esther Njom Nlend (ORCID: https://orcid.org/0000-0002-9881-8147)
- Catherine Nke Eyenga
- Rachel Kamgaing (ORCID: https://orcid.org/0000-0001-6354-1400)
- Alex Durand Nka (ORCID: https://orcid.org/0000-0002-9358-8661)
- Ezéchiel Ngoufack Jagni Semengue (ORCID: https://orcid.org/0000-0001-8768-2371)
- Vittorio Colizzi
- Nelly Kamgaing (ORCID: https://orcid.org/0000-0002-8974-5732)
- Jeremiah Efakika Gabisa
- Alexis Ndjolo (ORCID: https://orcid.org/0000-0002-4951-9271)
- Yagaï Bouba (ORCID: https://orcid.org/0000-0002-4187-683X)
- Rogers Ajeh (ORCID: https://orcid.org/0000-0002-5361-5063)
- Hyppolite K. Tchidjou (ORCID: https://orcid.org/0000-0001-9573-3845)
- Francis Ndongo Ateba
- Francesca Ceccherini‐Silberstein (ORCID: https://orcid.org/0000-0002-6024-5101)
- Aurelie Minelle Kengni Ngueko (ORCID: https://orcid.org/0000-0002-0733-5730)
- Alice Ketchaji
- Annie Nga Motazé
- Collins Ambe Chenwi (ORCID: https://orcid.org/0000-0002-6749-1436)
- Joseph Fokam
- Michel Carlos Tommo Tchouaket (ORCID: https://orcid.org/0000-0002-7186-8515)
- Aude Christelle Ka’e (ORCID: https://orcid.org/0000-0002-2381-4299)
- Carlo Federico Perno (ORCID: https://orcid.org/0000-0002-0825-5388)
- Naomi Karell Etame
- Larissa Gaëlle Moko Fotso
- Maria Mercedes Santoro
- Upal Roy (ORCID: https://orcid.org/0000-0002-0325-567X)
- Désiré Takou
- Krystel N. Zam
- Paul Ndombo Koki
- Samuel Martin Sosso
- Suzie Ndiang Tetang
- Lum Forgwei
- Felicité Noukayo
- Cynthia Ayafor
- Sandrine Claire Djupsa Njdeyep
- Dominik Guebiapsi Tameza
- Wiadamong Agabus
- Abdou Rahamani Gnambi
- Wome Basseck Roland
Institutions
- University of Rome Tor Vergata (IT)
- Université de Yaoundé I (CM)
- University of Douala (CM)
- The University of Texas Rio Grande Valley (US)
- Centre International De Reference Chantal Biya (CM)
- Saint Camillus International University of Health and Medical Sciences (IT)
- Centre Hospitalier Universitaire Amiens-Picardie (FR)
- Bambino Gesù Children's Hospital (IT)
- WWF Cameroon (CM)
- Ministry of Public Health (CM)
- University Teaching Hospital of Yaounde (CM)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- AIDS Research and Therapy
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1186/s12981-025-00826-5
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00