Evaluation of Stress-Dose Steroid Weaning Strategies in Patients Following Septic Shock
Rapid corticosteroid tapering in septic shock patients was associated with a reduced incidence of vasopressor reinitiation, shorter ICU and hospital stay, and a lower incidence of hypernatremia. These findings enhance our understanding of tapering strategies and suggest that rapid tapering (<72 hours) in septic shock may improve patient outcomes, informing future clinical guidelines.
Authors
- John Alex Toler
- Evan Westlake (ORCID: https://orcid.org/0000-0002-8735-7613)
- Jade M. Denninger (ORCID: https://orcid.org/0009-0005-1952-6509)
- Steven Skovran
Institutions
- Rex Hospital (US)
Publication Details
- Journal
- Annals of Pharmacotherapy
- Published
- 2025-12-07
- DOI
- https://doi.org/10.1177/10600280251385523
- Primary Topic
- Adrenal Hormones and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00