Therapeutic and Diagnostic Roles of MSC‐Derived Exosomes in Alzheimer's Disease
MSC-derived exosomes present a promising avenue for both therapeutic intervention and early diagnosis in AD, offering neuroprotective, anti-inflammatory, and pro-regenerative effects. However, further progress requires addressing challenges such as exosome isolation standardization, cargo characterization, and regulatory considerations to enable their translation into clinical practice.
Authors
- Anima Nanda (ORCID: https://orcid.org/0000-0003-3629-7937)
- Amit Sharma (ORCID: https://orcid.org/0000-0001-5037-1043)
- Bhavin Parekh
- Swati Mishra
- V. C. Patil (ORCID: https://orcid.org/0009-0000-3038-375X)
- Husni Farah (ORCID: https://orcid.org/0000-0001-8023-236X)
- Shaker Al‐Hasnaawei
- Renuka Jyothi‐S
- Manoj Kumar‐Mishra
Institutions
- Al-Ahliyya Amman University (JO)
- Jain University (IN)
- Long Island University (US)
- Siksha O Anusandhan University (IN)
- Iraqi University (IQ)
- University of Al-Qadisiyah (IQ)
- Institute of Medical Sciences and Sum Hospital (IN)
- Unity University College (ET)
- Sathyabama Institute of Science and Technology (IN)
- Salale University
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/brb3.71112
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00