Statistical Evidence for Bimodal Age Distribution in Pediatric Orchiopexy: Support for Congenital and Acquired Cryptorchidism Subtypes

Age-at-orchiopexy demonstrates statistically robust bimodality, with early (1.31 years) and late (6.28 years) components. This bimodal pattern is consistent with, and may correlate with, clinically hypothesized congenital and acquired cryptorchidism subtypes, but it does not by itself prove distinct biological entities. The intersection at 3.8 years may offer a quantitative reference point for age-specific management strategies and surveillance protocols and should be interpreted as hypothesis-generating rather than prescriptive.

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Publication Details

Journal
Cureus
Published
2025-12-07
DOI
https://doi.org/10.7759/cureus.98672
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Statistical Evidence for Bimodal Age Distribution in Pediatric Orchiopexy: Support for Congenital and Acquired Cryptorchidism Subtypes

Shinsuke Yoshizawa, Kensuke Ohashi, Keita Kogure
Cureus
Testicular diseases and treatments
article

Statistical Evidence for Bimodal Age Distribution in Pediatric Orchiopexy: Support for Congenital and Acquired Cryptorchidism Subtypes

Shinsuke Yoshizawa, Kensuke Ohashi, Keita Kogure
article en

Abstract

Age-at-orchiopexy demonstrates statistically robust bimodality, with early (1.31 years) and late (6.28 years) components. This bimodal pattern is consistent with, and may correlate with, clinically hypothesized congenital and acquired cryptorchidism subtypes, but it does not by itself prove distinct biological entities. The intersection at 3.8 years may offer a quantitative reference point for age-specific management strategies and surveillance protocols and should be interpreted as hypothesis-generating rather than prescriptive.

CureusVol. 17(12)
Saitama Children's Medical Center (JP)
Openalex Percentile: Top 42%
Testicular diseases and treatments
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