SWI/SNF complex alterations predict immunotherapy response in bladder cancer
SWI/SNF alterations define an immunotherapy-responsive stratification of UBC. The accompanying genotype-specific prognostic models provide a ready-to-test framework for guiding precision immunotherapy.
Authors
- Jun Jiang (ORCID: https://orcid.org/0000-0001-9408-2972)
- Qiang Ran (ORCID: https://orcid.org/0000-0002-4535-0229)
- Wei-Ming Luo (ORCID: https://orcid.org/0009-0002-6554-815X)
- Weihua Lan (ORCID: https://orcid.org/0000-0003-1186-195X)
- Jian Zhang (ORCID: https://orcid.org/0009-0009-4221-7113)
- Jun Zhang (ORCID: https://orcid.org/0000-0002-6601-9180)
- Yao Zhang (ORCID: https://orcid.org/0000-0001-5841-225X)
- Haitao Wang (ORCID: https://orcid.org/0000-0002-5947-6850)
- Qian Yan (ORCID: https://orcid.org/0009-0008-7483-0572)
- Jing Xu (ORCID: https://orcid.org/0000-0002-6530-5070)
- Yapeng Wang (ORCID: https://orcid.org/0000-0002-2923-1406)
- Qiuli Liu (ORCID: https://orcid.org/0000-0002-9532-5654)
- Y T Ji (ORCID: https://orcid.org/0009-0004-3850-0059)
- Hailin Zhu
- Yunpeng Ao
Institutions
- Army Medical University (CN)
- Daping Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1708324
- Primary Topic
- Chromatin Remodeling and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Centre Scientifique et Technique du Bâtiment