Bystander CD8+ conventional memory versus virtual memory T cells in the initial days post-Trypanosoma cruzi infection
These results challenge the view that only T<sub>MEM</sub> cells dominate early infection control. The equivalency of T<sub>VM</sub> and T<sub>MEM</sub> cells in parasite clearance suggests T<sub>VM</sub> cells are valuable innate-like contributors, providing rapid protection. Their numerical prevalence in unprimed individuals indicates T<sub>VM</sub> cells may be an underestimated component of early immunity.
Authors
- Fabio M. Cerbán (ORCID: https://orcid.org/0000-0001-6232-018X)
- María Estefania Viano (ORCID: https://orcid.org/0000-0001-5107-928X)
- Nicolás Leonel Lidon
- Ruth Eliana Baigorrí
- María Cecilia Rodriguez‐Galán (ORCID: https://orcid.org/0000-0002-5703-3116)
- María Pilar Aoki (ORCID: https://orcid.org/0000-0002-6897-7702)
- Cinthia Carolina Stempin (ORCID: https://orcid.org/0000-0002-8932-3409)
- Gastón Bergero
- Claudia Cristina Motrán (ORCID: https://orcid.org/0000-0002-8088-3901)
- Melisa Rocío Herrera
- Maria Gabriela Teixeira
Institutions
- Universidad Nacional de Córdoba (AR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1674964
- Primary Topic
- Trypanosoma species research and implications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agencia Nacional de Promoción Científica y Tecnológica
- Fondo para la Investigación Científica y Tecnológica