KLF2-mediated activation of Nrf2-HO-1 pathway modulates microglia/macrophage polarization post-ischemic stroke
The study unveils KLF2 is neuroprotection and could promote microglia/macrophage polarization from the M1 to M2 phenotype in IS by activating the Nrf2-HO-1 pathway.
Authors
- Gui-Yuan Huang (ORCID: https://orcid.org/0009-0001-4897-2664)
- Hongmiao Tao (ORCID: https://orcid.org/0000-0001-7880-7291)
- Yuanyuan Wu
Institutions
- Jinhua University of Vocational Technology (CN)
Publication Details
- Journal
- Neurological Research
- Published
- 2025-12-07
- DOI
- https://doi.org/10.1080/01616412.2025.2597830
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 0.00