Molecular transmission network characteristics and high-risk transmission analysis of newly reported HIV-1 subjects in Nantong, China
The HIV-1 epidemic in Nantong was characterized by the increasing dominance of CRF07_BC, rising pretreatment drug resistance, and extensive inter-city molecular clustering. Older people, particularly older men, are emerging as a critical population sustaining local transmission. These findings highlight the need for continuous molecular surveillance and region-specific prevention strategies tailored to high-risk groups to mitigate further HIV-1 spread.
Authors
- A.C.N. Chen
- Xun Zhuang (ORCID: https://orcid.org/0000-0002-3974-8193)
- Hongli Xia
- Xiaoyi Zhou (ORCID: https://orcid.org/0000-0002-8926-9078)
- Dongyang Wang (ORCID: https://orcid.org/0000-0002-7182-6323)
- Kai Liu (ORCID: https://orcid.org/0000-0002-8014-2310)
- Ping Zhu (ORCID: https://orcid.org/0000-0001-6488-064X)
- Tingting Yuan (ORCID: https://orcid.org/0000-0003-4942-6646)
Institutions
- Nantong University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1716273
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jiangsu Commission of Health
- Government of Jiangsu Province