The effect of disulfidptosis induced by glucose starvation in SLC7A11high ovarian cancer cells
Glucose starvation induces high SLC7A11 expression in OC cells, resulting in cell death. This type of cell death is associated with NADPH depletion in the cell and the accumulation of disulfides. Therefore, it is considered that disulfidptosis may occur in SLC7A11<sup>high</sup> OC cells under glucose starvation conditions.
Authors
- Wenjing Shi (ORCID: https://orcid.org/0000-0002-0867-5569)
- Yuhua Ou (ORCID: https://orcid.org/0000-0003-4720-7677)
- Yating Chen (ORCID: https://orcid.org/0000-0003-3299-0566)
Institutions
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3389/fcell.2025.1608150
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province