Body composition changes in women with early breast cancer after adjuvant treatment: a systematic review

This systematic review identified consistent increases in total fat mass and visceral fat across the included studies, regardless of whether the treatment involved chemotherapy, endocrine therapy or a combination of both. In contrast, findings related to lean body mass were considerably less consistent. The results highlight the potential implications following breast cancer treatment and emphasise the importance of metabolic monitoring, diet and exercise to increase quality of life and prevent recurrence. This review also highlights the need for more research on the topic, as the included studies exhibit substantial heterogeneity, making it difficult to draw definitive conclusions.

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Publication Details

Journal
Acta Oncologica
Published
2025-12-07
DOI
https://doi.org/10.2340/1651-226x.2025.44707
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
0.00

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article

Body composition changes in women with early breast cancer after adjuvant treatment: a systematic review

Trine Lund-Jacobsen, Kristian Buch‐Larsen, Caroline Kistorp, Peter Schwarz et al.
Acta Oncologica
Cancer Risks and Factors
article

Body composition changes in women with early breast cancer after adjuvant treatment: a systematic review

Trine Lund-Jacobsen, Kristian Buch‐Larsen, Caroline Kistorp, Peter Schwarz, Simone Diedrichsen Marstrand, August Nielsen, Valdemar Mendez
article en

Abstract

This systematic review identified consistent increases in total fat mass and visceral fat across the included studies, regardless of whether the treatment involved chemotherapy, endocrine therapy or a combination of both. In contrast, findings related to lean body mass were considerably less consistent. The results highlight the potential implications following breast cancer treatment and emphasise the importance of metabolic monitoring, diet and exercise to increase quality of life and prevent recurrence. This review also highlights the need for more research on the topic, as the included studies exhibit substantial heterogeneity, making it difficult to draw definitive conclusions.

Acta OncologicaVol. 64
Copenhagen University Hospital (DK)
University of California, San Francisco
Openalex Percentile: Top 46%
Cancer Risks and Factors
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