Ovarian Immature Teratoma with Gliomatosis Peritonei and Nodal Gliomatosis Metastasis: A Case Report

Gliomatosis peritonei (GP) is a rare condition of mature glial tissue within the peritoneum. GP has been reported in approximately 100 cases worldwide, and it rarely occurs in young women or in patients with ovarian mature or immature teratomas during childhood. In patients with ovarian immature teratoma (OIT) combined with gliomatosis peritonei, the tumor is typically large and is often detected intraoperatively. Its neuroglial component may not only spread within the peritoneum but also metastasize via the lymphatic vessels. Pathologically confirmed lymph nodes containing mature neuroglial components and positive for glial fibrillary acidic protein (GFAP) are consistent with nodal gliomatosis (NG). In this report, we present a case of gliomatosis associated with OIT combined with GP, which involves lymph nodes.