Analysis of the Clinicopathological Characteristics of Different Molecular Subtypes in Endometrial Cancer: A Retrospective Single Center Study

The distribution of molecular subtypes among patients with different histopathological types shows significant differences. The proportion of POLE mutant type in endometrioid carcinoma is higher than that of other histological types, while the proportion of p53 abnormal type is relatively high in high-grade and highly invasive histological types such as serous carcinoma and clear cell carcinoma. It provides valuable reference for guiding the diagnosis and treatment of endometrial cancer by integrating molecular subtypes with clinicopathological characteristics.