A Rare Case of Gastric Glomangioma Mimicking a Gastrointestinal Stromal Tumor (GIST)

Glomus tumors are rare mesenchymal neoplasms originating from modified smooth muscle cells involved in thermoregulation. Although typically located in peripheral soft tissues, their presence in the stomach is uncommon and may lead to diagnostic difficulties. This report presents a rare case of gastric glomangioma that clinically and radiologically mimicked a gastrointestinal stromal tumor. A 61-year-old woman presented in July 2024 with a three-month history of epigastric pain, nausea, and abdominal bloating. Upper gastrointestinal endoscopy revealed a submucosal lesion at the incisura angularis resembling a stromal tumor. Endoscopic ultrasonography demonstrated a well-circumscribed, submucosal, iso-hypoechoic mass measuring 19.5×11.3 mm. Due to persistent symptoms, surgical excision was performed, and the mass was completely removed with negative margins. Histopathological evaluation confirmed the diagnosis of a gastric glomus tumor. The postoperative course was uneventful, and no complications were observed during follow-up. This case emphasizes the importance of including glomus tumors in the differential diagnosis of subepithelial gastric lesions, particularly when imaging findings overlap with more common entities. Increased clinical awareness may improve preoperative diagnostic accuracy and support appropriate management strategies.