A novel approach to enhance beta-sitosterol bioavailability isolated from Jurinea macrocephala (a high-altitude) plant in biodegradable chitosan against lung cancer

Chitosan-encapsulated nano β-sitosterol demonstrated enhanced solubility, sustained release, and improved therapeutic efficacy against lung cancer, highlighting its potential as a promising delivery system for lung cancer with improved therapeutic outcomes.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-12-08
DOI
https://doi.org/10.3389/fonc.2025.1659465
Primary Topic
Natural product bioactivities and synthesis
Type
article
Field-Weighted Citation Impact
0.00

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article

A novel approach to enhance beta-sitosterol bioavailability isolated from Jurinea macrocephala (a high-altitude) plant in biodegradable chitosan against lung cancer

Madhulika Bhagat, Monica Sangral, Ankita Singh, Ashutosh Gupta
Frontiers in Oncology
Natural product bioactivities and synthesis
article

A novel approach to enhance beta-sitosterol bioavailability isolated from Jurinea macrocephala (a high-altitude) plant in biodegradable chitosan against lung cancer

Madhulika Bhagat, Monica Sangral, Ankita Singh, Ashutosh Gupta
article en

Abstract

Chitosan-encapsulated nano β-sitosterol demonstrated enhanced solubility, sustained release, and improved therapeutic efficacy against lung cancer, highlighting its potential as a promising delivery system for lung cancer with improved therapeutic outcomes.

Frontiers in OncologyVol. 15
University of Jammu (IN), Government Medical College (IN)
Department of Biotechnology, Ministry of Science and Technology, India, Department of Science and Technology, Ministry of Science and Technology, India, Science and Engineering Research Board
Openalex Percentile: Top 65%
Natural product bioactivities and synthesis
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