Autoimmune cerebellopyramidal syndrome as a complex form of autoimmune cerebellar ataxia: a cohort study
Autoimmune cerebellopyramidal syndrome represents a distinct and complex ACA phenotype, characterized by unique clinical and imaging features, CSF abnormalities indicative of a more pronounced autoimmune response, and a higher relapse rate. Comprehensive evaluation and long-term maintenance immunotherapy may be warranted in these patients.
Authors
- Mange Liu
- Siyuan Fan (ORCID: https://orcid.org/0000-0001-8016-9110)
- Hongzhi Guan (ORCID: https://orcid.org/0000-0001-6754-9688)
- Le Zhang (ORCID: https://orcid.org/0000-0003-4706-9243)
- Haitao Ren (ORCID: https://orcid.org/0000-0002-1911-5858)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1724439
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese Academy of Medical Sciences
- Peking Union Medical College
- Bijzonder Onderzoeksfonds UGent