The transcriptome of CD14 <sup>+</sup> CD163 <sup>-</sup> HLA-DR <sup>low</sup> monocytes predicts mortality in Idiopathic Pulmonary Fibrosis
The transcriptome of CD14<sup>+</sup>CD163<sup>-</sup>HLA-DR<sup>low</sup> monocytes is associated with increased mortality in patients with IPF. Its reversal should be investigated as a precision-based therapy in IPF.
Authors
- Minxue Jia (ORCID: https://orcid.org/0000-0001-9305-1218)
- Τheodoros Karampitsakos (ORCID: https://orcid.org/0000-0003-0804-6292)
- Imre Noth (ORCID: https://orcid.org/0000-0001-9846-5030)
- Michael Kreuter (ORCID: https://orcid.org/0000-0003-4402-2159)
- Jose D. Herazo‐Maya (ORCID: https://orcid.org/0000-0002-8129-6346)
- Erica L. Herzog (ORCID: https://orcid.org/0000-0002-7508-8575)
- Antje Prasse (ORCID: https://orcid.org/0000-0002-7336-7458)
- Stephen B. Liggett (ORCID: https://orcid.org/0000-0002-0128-3669)
- Αrgyris Τzouvelekis (ORCID: https://orcid.org/0000-0002-0392-655X)
- Wonder P. Drake (ORCID: https://orcid.org/0000-0001-9406-3130)
- Panayiotis V. Benos (ORCID: https://orcid.org/0000-0003-3172-3132)
- Brenda Juan-Guardela
- Joe G. N. Garcia (ORCID: https://orcid.org/0000-0002-6934-0420)
- Carole Y. Perrot (ORCID: https://orcid.org/0000-0003-4603-4436)
- Bochra Tourki
- Marc A. Schneider (ORCID: https://orcid.org/0000-0001-8269-3821)
- Ioannis Vamvakaris (ORCID: https://orcid.org/0000-0002-2917-7155)
- Avraham Unterman (ORCID: https://orcid.org/0000-0003-0965-3326)
- Naftali Kaminski (ORCID: https://orcid.org/0000-0001-5917-4601)
- Debabrata Bandyopadhyay (ORCID: https://orcid.org/0000-0002-5323-9061)
- Amy Zhao (ORCID: https://orcid.org/0000-0003-0481-2885)
- Zainab Fatima (ORCID: https://orcid.org/0009-0000-5058-4954)
- Bogdan Visinescu
- Tamer Fadli
Institutions
- Scripps Research Institute (US)
- University of Maryland, Baltimore (US)
- University of Pittsburgh (US)
- Johannes Gutenberg University Mainz (DE)
- Heidelberg University (DE)
- University of South Florida (US)
- Tel Aviv Sourasky Medical Center (IL)
- General University Hospital of Patras (GR)
- University Hospital Heidelberg (DE)
- Yale University (US)
- University of Florida (US)
- Medizinische Hochschule Hannover (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- German Center for Lung Research (DE)
- Sotiria General Hospital (GR)
- University of Virginia (US)
- Columbia University (US)
Publication Details
- Journal
- European Respiratory Journal
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1183/13993003.00804-2025
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00