Can lymphocytic toxicity be induced by radiation dose to the bowel bag in whole pelvic radiotherapy?
Radiation dose to the bowel bag independently predicts severe lymphocytopenia during pelvic radiotherapy. These findings suggest that dose constraints to the bowel bag should be considered alongside bone marrow sparing techniques to preserve hematopoietic function. Prospective validation and development of bowel bag dose-volume guidelines are warranted.
Authors
- Yeon‐Sil Kim
- Kyu Hye Choi (ORCID: https://orcid.org/0000-0001-6446-6377)
- Wonmo Sung (ORCID: https://orcid.org/0000-0002-0172-0646)
- Ji Hyun Hong (ORCID: https://orcid.org/0000-0002-6237-891X)
- Myung S. Ko (ORCID: https://orcid.org/0000-0001-9176-5399)
- Seok Hyun Son (ORCID: https://orcid.org/0000-0002-2577-1915)
- Hong-Seok Jang (ORCID: https://orcid.org/0009-0000-5299-0761)
- Young‐Nam Kang
- Byung-Ock Choi
Institutions
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Radiation Oncology Journal
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3857/roj.2025.00220
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Catholic University of Korea
- Seoul St. Mary's Hospital, Catholic University of Korea