Genomic divergence between matched primary and metastatic tumors across cancer types: a pan-cancer analysis of 5,692 samples

Compared with primary tumors, metastatic tumors demonstrated small but consistent genomic differences. These findings varied across cancer types and may reflect changes associated with the evolutionary transition from primary to metastatic disease.

Authors

Publication Details

Journal
Expert Review of Anticancer Therapy
Published
2025-12-08
DOI
https://doi.org/10.1080/14737140.2025.2601769
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Genomic divergence between matched primary and metastatic tumors across cancer types: a pan-cancer analysis of 5,692 samples

Yakup Ergün
Expert Review of Anticancer Therapy
Cancer Genomics and Diagnostics
article

Genomic divergence between matched primary and metastatic tumors across cancer types: a pan-cancer analysis of 5,692 samples

Yakup Ergün
article en

Abstract

Compared with primary tumors, metastatic tumors demonstrated small but consistent genomic differences. These findings varied across cancer types and may reflect changes associated with the evolutionary transition from primary to metastatic disease.

Expert Review of Anticancer Therapy
Openalex Percentile: Top 52%
Cancer Genomics and Diagnostics
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Genomic divergence between matched primary and metastatic tumors across cancer types: a pan-cancer analysis of 5,692 samples — Yakup Ergün · Expert Review of Anticancer Therapy (2025) | TGRS Research Map | TGRS