Effect of Weight‐Neutral Treatment With Semaglutide or Tirzepatide on β‐Cell Identity in <i>db</i> / <i>db</i> Mice
The findings highlight that the early glucose-lowering effects of semaglutide and tirzepatide in db/db mice occur independently of changes to β-cell identity.
Authors
- Wendy M. McKimpson (ORCID: https://orcid.org/0000-0002-2262-5998)
- Wen Du (ORCID: https://orcid.org/0000-0002-8138-774X)
- Jinsook Son (ORCID: https://orcid.org/0000-0002-0836-2626)
- Zhaobin Deng (ORCID: https://orcid.org/0009-0009-4278-8178)
- Qingli Liu (ORCID: https://orcid.org/0000-0001-7684-7118)
- Dongxu Zheng (ORCID: https://orcid.org/0000-0003-1068-8403)
- Domenico Accili
Institutions
- Leiden University Medical Center (NL)
- Columbia University (US)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Acta Physiologica
- Published
- 2025-12-07
- DOI
- https://doi.org/10.1111/apha.70141
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00