Butylphthalide enhances neurorestoration following ischemic stroke by restructuring microvasculature through vimentin modulation
Our study reveals NBP can effectively treat ischemic stroke by targeting VIM to revitalise microvasculature, facilitating neurorestoration.
Authors
- Guibo Sun (ORCID: https://orcid.org/0000-0002-9476-1243)
- Li Hua Cao (ORCID: https://orcid.org/0000-0003-1742-9877)
- Jingxue Ye (ORCID: https://orcid.org/0000-0002-0301-7305)
- Haochen Xie
- Ruimao Zheng (ORCID: https://orcid.org/0000-0001-7404-2607)
- S. Zhang (ORCID: https://orcid.org/0000-0003-0644-7930)
- Tian Yu (ORCID: https://orcid.org/0000-0002-2443-9961)
- Meng Qin (ORCID: https://orcid.org/0000-0002-5448-2477)
- Shiyi Sun
- Haiyan Xiao (ORCID: https://orcid.org/0000-0003-2878-337X)
- Chenwei Zuo
- Min Wang (ORCID: https://orcid.org/0000-0003-2052-199X)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jare.2025.11.068
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00