Low-Dose Radiation Therapy (LDRT) for Lymphatic Obliteration in Persistent Chylous Ascites: A Case Report

Chylous ascites is a rare postoperative complication, typically associated with extensive abdominal procedures and caused by inadvertent injury to the retroperitoneal lymphatic vessels. Its management represents a therapeutic challenge, particularly in cases refractory to conventional strategies. We present the case of a patient with persistent lymphatic leakage following retroperitoneal lymphadenectomy for recurrent testicular cancer, who failed multiple standard interventions. Given the refractory nature of the condition, low-dose external beam radiotherapy was administered, resulting in complete resolution with no recurrence at two-year follow-up. This case highlights radiotherapy as a potentially effective therapeutic option for the management of lymphatic fistulas.

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Journal
Cureus
Published
2025-12-07
DOI
https://doi.org/10.7759/cureus.98646
Primary Topic
Lymphatic Disorders and Treatments
Type
article
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article

Low-Dose Radiation Therapy (LDRT) for Lymphatic Obliteration in Persistent Chylous Ascites: A Case Report

Simone Garzon, Stephanie Giraldo, Andrés F Ramírez, Eduardo Guerrero Lizcano et al.
Cureus
Lymphatic Disorders and Treatments
article

Low-Dose Radiation Therapy (LDRT) for Lymphatic Obliteration in Persistent Chylous Ascites: A Case Report

Simone Garzon, Stephanie Giraldo, Andrés F Ramírez, Eduardo Guerrero Lizcano, Yuli Natalia Otero Pabon, Javier Rodriguez Corredor
article en

Abstract

Chylous ascites is a rare postoperative complication, typically associated with extensive abdominal procedures and caused by inadvertent injury to the retroperitoneal lymphatic vessels. Its management represents a therapeutic challenge, particularly in cases refractory to conventional strategies. We present the case of a patient with persistent lymphatic leakage following retroperitoneal lymphadenectomy for recurrent testicular cancer, who failed multiple standard interventions. Given the refractory nature of the condition, low-dose external beam radiotherapy was administered, resulting in complete resolution with no recurrence at two-year follow-up. This case highlights radiotherapy as a potentially effective therapeutic option for the management of lymphatic fistulas.

CureusVol. 17(12)
Instituto Nacional de Cancerología (CO)
Openalex Percentile: Top 42%
Lymphatic Disorders and Treatments
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Low-Dose Radiation Therapy (LDRT) for Lymphatic Obliteration in Persistent Chylous Ascites: A Case Report — Simone Garzon, Stephanie Giraldo, et al. · Cureus (2025) | TGRS Research Map | TGRS