A Meta‐analysis of Functional Outcomes and Recovery Metrics Comparing Transoral Robotic Surgery and (Chemo)Radiotherapy
This review presents the most extensive examination to date of swallowing performance and recovery metrics in controlled trials of transoral robotic surgery versus (chemo)radiotherapy. Our findings show that transoral robotic surgery shows promise in managing difficult anatomical areas and low-grade tumors. However, methodological inconsistencies were noted between included studies, particularly in eligibility criteria and human papillomavirus p16 status. Consensus statements and/or guidelines on stratification and reporting of patients may aid in reducing this heterogeneity, while further randomized controlled trials may improve our understanding and guide the development of clinical guidelines on treatment choice.
Authors
- Muzammil Arif Din Abdul Jabbar (ORCID: https://orcid.org/0000-0002-4882-8486)
- Amit Gupta (ORCID: https://orcid.org/0000-0001-6468-1472)
- Eleanor Barker (ORCID: https://orcid.org/0000-0001-5472-2496)
- Manaf Khatib (ORCID: https://orcid.org/0000-0002-5205-7856)
- Simpson Shiu Chung Tam (ORCID: https://orcid.org/0000-0002-1477-6729)
- Anant Patel (ORCID: https://orcid.org/0000-0002-4515-6362)
- George Mochloulis
- Nihal Sogandji (ORCID: https://orcid.org/0000-0001-6982-8672)
- Shazia Absar (ORCID: https://orcid.org/0009-0008-8803-0496)
- J. Adam Tooze (ORCID: https://orcid.org/0000-0002-0694-9095)
- Mikesh Kalpesh Patel (ORCID: https://orcid.org/0009-0007-6877-8571)
Institutions
- University of Cambridge (GB)
- Health First (US)
- Bridge University (SS)
- Mount Vernon Cancer Centre (GB)
- East and North Hertfordshire NHS Trust (GB)
- Public Library of Science (GB)
Publication Details
- Journal
- Otolaryngology
- Published
- 2025-12-07
- DOI
- https://doi.org/10.1002/ohn.70069
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00