Effect and mechanism of chemokine receptor 1 in airway inflammation in a mouse model of chronic obstructive pulmonary disease

CCR1 aggravates the progression of COPD mice by activating JAK/STAT3/NF-κB signaling. This study has the potential to provide theoretical evidence for the diagnosis and therapeutic strategies of cigarette smoke-induced inflammation in COPD patients.

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Publication Details

Journal
Experimental Lung Research
Published
2025-12-07
DOI
https://doi.org/10.1080/01902148.2025.2593254
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Effect and mechanism of chemokine receptor 1 in airway inflammation in a mouse model of chronic obstructive pulmonary disease

Kaishun Zhao, Yanfang Yu, Wei Wei, Zhen Wang et al.
Experimental Lung Research
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Effect and mechanism of chemokine receptor 1 in airway inflammation in a mouse model of chronic obstructive pulmonary disease

Kaishun Zhao, Yanfang Yu, Wei Wei, Zhen Wang, Suzhen Ju
article en

Abstract

CCR1 aggravates the progression of COPD mice by activating JAK/STAT3/NF-κB signaling. This study has the potential to provide theoretical evidence for the diagnosis and therapeutic strategies of cigarette smoke-induced inflammation in COPD patients.

Experimental Lung ResearchVol. 51(1)
Jiading District Central Hospital (CN), Shanghai University of Medicine and Health Sciences (CN)
Openalex Percentile: Top 43%
Chronic Obstructive Pulmonary Disease (COPD) Research
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