Scoping review of the opportunities to escape oral cancer

Background: With a high rate of death and morbidity, oral cancer ranks as the sixteenth most prevalent cancer worldwide. According to the Global Cancer Observatory (GLOBOCAN) of the International Agency for Research on Cancer (IARC), there were 177,757 oral cancer-related deaths and 377,713 new cases globally in 2020. Oral cancer in India comprises 45% of the global disease burden. Men (incidence rate: 13.1 per 100,000) are 2.62 times more likely to be affected by head and neck cancer than women (5 per 100,000) and experience double the corresponding mortality rates. The high prevalence, incidence, and excruciating nature of the disease necessitated this review to outline potential precautions and prophylactic interventions to be undertaken to prevent this agonizing and highly fatal disease in order to sensitize healthcare workers and train them to fight this disease. Methods: The search analysis from PubMed, the World Health Organisation (WHO) International Clinical Trials Registry, Cochrane Reviews, and CENTRAL yielded a list of comprehensive strategies used in different geographic locations to prevent this deleterious health issue. Results: The results include evidence of interventions that have successfully prevented oral cancer in different sections of the population. In addition to controlling tobacco use and herpes virus infection, these interventions include community health programs, primary healthcare workers and dentists, chemopreventive agents, herbal extracts, and artificial intelligence models. Conclusion: Oral health is one factor affecting well-being, so a preventive approach must be considered to ensure its achievement.

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Publication Details

Journal
Journal of Oral Health and Oral Epidemiology
Published
2025-10-20
DOI
https://doi.org/10.34172/johoe.2401.1617
Primary Topic
Head and Neck Cancer Studies
Type
article
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article

Scoping review of the opportunities to escape oral cancer

Nisha Daniel
Journal of Oral Health and Oral Epidemiology
Head and Neck Cancer Studies
article

Scoping review of the opportunities to escape oral cancer

Nisha Daniel
article en

Abstract

Background: With a high rate of death and morbidity, oral cancer ranks as the sixteenth most prevalent cancer worldwide. According to the Global Cancer Observatory (GLOBOCAN) of the International Agency for Research on Cancer (IARC), there were 177,757 oral cancer-related deaths and 377,713 new cases globally in 2020. Oral cancer in India comprises 45% of the global disease burden. Men (incidence rate: 13.1 per 100,000) are 2.62 times more likely to be affected by head and neck cancer than women (5 per 100,000) and experience double the corresponding mortality rates. The high prevalence, incidence, and excruciating nature of the disease necessitated this review to outline potential precautions and prophylactic interventions to be undertaken to prevent this agonizing and highly fatal disease in order to sensitize healthcare workers and train them to fight this disease. Methods: The search analysis from PubMed, the World Health Organisation (WHO) International Clinical Trials Registry, Cochrane Reviews, and CENTRAL yielded a list of comprehensive strategies used in different geographic locations to prevent this deleterious health issue. Results: The results include evidence of interventions that have successfully prevented oral cancer in different sections of the population. In addition to controlling tobacco use and herpes virus infection, these interventions include community health programs, primary healthcare workers and dentists, chemopreventive agents, herbal extracts, and artificial intelligence models. Conclusion: Oral health is one factor affecting well-being, so a preventive approach must be considered to ensure its achievement.

Journal of Oral Health and Oral EpidemiologyVol. 14
Medical Research Scotland (GB), The Queen's Medical Research Institute (GB)
Openalex Percentile: Top 46%
Head and Neck Cancer Studies
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