Stress hyperglycemia ratio and physical frailty in HFpEF
A higher SHR was independently associated with poorer physical function in frail older adults with HFpEF. These findings suggest that stress-related dysglycemia may contribute to functional decline in this population, highlighting the potential utility of SHR as a metabolic marker of frailty severity and cardiovascular vulnerability.
Authors
- Antonio Rainone
- Guido Iaccarino (ORCID: https://orcid.org/0000-0002-8997-835X)
- Gaetano Santulli (ORCID: https://orcid.org/0000-0001-7231-375X)
- Klara Komici
- Gaetano Macina
- Germano Guerra (ORCID: https://orcid.org/0000-0002-4342-962X)
- Gianluca Gennarelli (ORCID: https://orcid.org/0000-0003-4390-9428)
- Urna Kansakar (ORCID: https://orcid.org/0000-0001-5847-0521)
- Pasquale Mone (ORCID: https://orcid.org/0000-0001-6267-5845)
- Gianluca Testa (ORCID: https://orcid.org/0000-0001-5944-4341)
- Marco Di Mauro (ORCID: https://orcid.org/0000-0002-1532-8274)
- Tommaso Dazzetti
Institutions
- University of Molise (IT)
- Albert Einstein College of Medicine (US)
- Feinstein Institute for Medical Research (US)
- Institute of Food Science (IT)
- Federico II University Hospital (IT)
- Casa di cura Pierangeli (IT)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-12-07
- DOI
- https://doi.org/10.1186/s12933-025-03020-z
- Citations
- 1
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 1.22