Therapeutic drug monitoring of amikacin in Chinese premature infant: a population pharmacokinetic analysis and dosage optimization
Weight, postmenstrual age and renal function have significant influence on the PK of amikacin in Chinese premature infants. The optimal dosage regimens might provide an alternative choice for premature infants in China in the therapy of amikacin.
Authors
- Jinhui Xu (ORCID: https://orcid.org/0000-0001-5730-9429)
- Zongtai Feng (ORCID: https://orcid.org/0009-0003-8860-5724)
- Yanxia Yu (ORCID: https://orcid.org/0000-0001-6105-0114)
- Qian Zhang (ORCID: https://orcid.org/0000-0002-6889-7112)
- Yan Huang (ORCID: https://orcid.org/0000-0002-6559-6234)
- Jingjing Li (ORCID: https://orcid.org/0000-0003-3636-0537)
- Jiahui Li (ORCID: https://orcid.org/0000-0003-4278-8222)
- Mi Zhou (ORCID: https://orcid.org/0000-0001-8453-4648)
- Lian Tang (ORCID: https://orcid.org/0000-0002-8059-8166)
- Zuming Yang
- Lufen Duan
Institutions
- Soochow University (CN)
- Suzhou Municipal Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1186/s12879-025-11747-z
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00