Iron-Catalyzed 4-Azafluorenone Synthesis from Oxime Esters and 1,3-Indanedione-Derived Enones
We develop an iron-catalyzed formal [3 + 3] annulation approach for the construction of 4-azafluorenones. This method employs oxime esters and 1,3-indanedione-derived enones as easily available starting materials, which efficiently furnish a series of structurally diverse 4-azafluorenones with good functional group tolerance.
Authors
- Kun Jiang (ORCID: https://orcid.org/0000-0003-3148-5058)
- Ye Wei (ORCID: https://orcid.org/0000-0001-9970-4152)
- Ning Yu
- Yunbo Yang (ORCID: https://orcid.org/0000-0001-9061-9883)
- Yuqiang Zhou
- Jia‐Hao Zhou (ORCID: https://orcid.org/0000-0001-8874-7405)
- Mei-Jun Zheng
Institutions
- Southwest University (CN)
- Chongqing Municipal Government (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1021/acs.joc.5c02541
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00