Impact of Growth-promoting Therapies on Puberty, Growth, and Final Height in Classical 21-hydroxylase Deficiency.
Patients with 21-OHD had diminished FH despite early diagnosis. Puberty in classical 21-OHD had an earlier onset, slower tempo, and prolonged duration, especially in girls, in which GPTs are less effective in promoting height. The management of pubertal growth needs a personalized approach in patients with classical 21-OHD.
Authors
- Şükran Poyrazoğlu (ORCID: https://orcid.org/0000-0001-6806-9678)
- Hasan Önal (ORCID: https://orcid.org/0000-0001-9676-7086)
- Firdevs Baş (ORCID: https://orcid.org/0000-0001-9689-4464)
- Gizem Çilsaat
- Afshin Moniri (ORCID: https://orcid.org/0000-0001-7237-8940)
- Rüveyde Bundak (ORCID: https://orcid.org/0000-0001-5097-6448)
- Tülay Güran (ORCID: https://orcid.org/0000-0003-2658-6866)
- Zehra Oya Uyguner (ORCID: https://orcid.org/0000-0002-2035-4338)
- Melek Yıldız (ORCID: https://orcid.org/0000-0002-6603-2983)
- Güven Toksoy (ORCID: https://orcid.org/0000-0002-8103-9980)
- Saygın Abalı (ORCID: https://orcid.org/0000-0001-6552-2801)
- Feyza Darendelıler (ORCID: https://orcid.org/0000-0003-4786-0780)
- Abdullah Bereket (ORCID: https://orcid.org/0000-0002-6584-9043)
- Serap Turan (ORCID: https://orcid.org/0000-0002-5172-5402)
- Zehra Yavaş Abalı (ORCID: https://orcid.org/0000-0002-8971-6181)
Institutions
- University of Health Science (KH)
- Sağlık Bilimleri Üniversitesi (TR)
- Kent Hastanesi (TR)
- University of Kyrenia (CY)
- Istanbul University (TR)
- Marmara University (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- PubMed
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1210/clinem/dgaf612
- Citations
- 1
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81