Cranioplasty after surgical site infection in brain tumor patients: insights from a 15-year Swedish multicenter study

Cranioplasty after bone flap removal due to SSI following brain tumor surgery was associated with a substantial risk of implant failure despite reconstruction of relatively small cranial defects. Predictive factors for implant failure were limited, suggesting that unmeasured variables, such as soft tissue conditions, might play a significant role in these procedures. Given the high rate of implant removal and limited survival among patients with high-grade tumors, careful patient selection and individualized decision-making are essential.

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Publication Details

Journal
Journal of neurosurgery
Published
2025-12-08
DOI
https://doi.org/10.3171/2025.7.jns251301
Primary Topic
Traumatic Brain Injury and Neurovascular Disturbances
Type
article
Field-Weighted Citation Impact
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article

Cranioplasty after surgical site infection in brain tumor patients: insights from a 15-year Swedish multicenter study

Klas Holmgren, Alba Corell, Richard Ågren, Robert Nilsson et al.
Journal of neurosurgery
Traumatic Brain Injury and Neurovascular Disturbances
article

Cranioplasty after surgical site infection in brain tumor patients: insights from a 15-year Swedish multicenter study

Klas Holmgren, Alba Corell, Richard Ågren, Robert Nilsson, Teodor Svedung Wettervik, Jimmy Sundblom, Alexander Fletcher‐Sandersjöö, Lars Linder, Peter Lindvall, Francesco Latini, Emilia Muncan, Bjartur Sæmundsson
article en

Abstract

Cranioplasty after bone flap removal due to SSI following brain tumor surgery was associated with a substantial risk of implant failure despite reconstruction of relatively small cranial defects. Predictive factors for implant failure were limited, suggesting that unmeasured variables, such as soft tissue conditions, might play a significant role in these procedures. Given the high rate of implant removal and limited survival among patients with high-grade tumors, careful patient selection and individualized decision-making are essential.

Journal of neurosurgeryVol. 144(3)
Uppsala University (SE), Karolinska University Hospital (SE), Sahlgrenska University Hospital (SE), Karolinska Institutet (SE), Department of Medical Sciences (RU), University of Gothenburg (SE), Umeå University (SE)
Openalex Percentile: Top 47%
Traumatic Brain Injury and Neurovascular Disturbances
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Cranioplasty after surgical site infection in brain tumor patients: insights from a 15-year Swedish multicenter study — Klas Holmgren, Alba Corell, et al. · Journal of neurosurgery (2025) | TGRS Research Map | TGRS