A Comparative Study of Topical 2% Diltiazem Versus Lateral Internal Sphincterotomy in the Treatment of Fissure-in-Ano

Study concludes that lateral internal sphincterotomy remains the gold standard treatment for chronic anal fissure. Diltiazem therapy is a good alternative for patients who refused surgery or prefer medical line of treatment and can be used as a first choice in management of chronic fissures.

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Publication Details

Journal
Cureus
Published
2025-12-07
DOI
https://doi.org/10.7759/cureus.98615
Primary Topic
Anorectal Disease Treatments and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

A Comparative Study of Topical 2% Diltiazem Versus Lateral Internal Sphincterotomy in the Treatment of Fissure-in-Ano

Simhadri Siripurapu, Kusa R Pyla, Rajani Devi Gosala, Sri Satya Sudha Tula et al.
Cureus
Anorectal Disease Treatments and Outcomes
article

A Comparative Study of Topical 2% Diltiazem Versus Lateral Internal Sphincterotomy in the Treatment of Fissure-in-Ano

Simhadri Siripurapu, Kusa R Pyla, Rajani Devi Gosala, Sri Satya Sudha Tula, Vijaya Petta
article en

Abstract

Study concludes that lateral internal sphincterotomy remains the gold standard treatment for chronic anal fissure. Diltiazem therapy is a good alternative for patients who refused surgery or prefer medical line of treatment and can be used as a first choice in management of chronic fissures.

CureusVol. 17(12)
Rangaraya Medical College (IN)
Openalex Percentile: Top 42%
Anorectal Disease Treatments and Outcomes
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A Comparative Study of Topical 2% Diltiazem Versus Lateral Internal Sphincterotomy in the Treatment of Fissure-in-Ano — Simhadri Siripurapu, Kusa R Pyla, et al. · Cureus (2025) | TGRS Research Map | TGRS