The Valvular Heart Disease in Women (VHD-W) Registry: a global initiative to address gender disparities in management and outcomes
The VHD-W is an international, multicenter, non-commercial, investigator-initiated, multipurpose registry endorsed by the European Association of Cardiovascular Imaging. The VHD-W involves adult patients with moderate-to-severe valvular heart disease admitted, either urgently or electively, to the cardiology inpatient service. The study aims to enrol 800 patients, balanced between genders, across more than 70 centres worldwide, over a 6-month period from the registry inception in March 2024 until the end of December 2025. Data will be collected at inpatient admission, inpatient discharge, and 1-year follow-up, including demographics, medical history, physical examination, biomarkers, echocardiography, other imaging results, and management. Conclusion The VHD-W is the first registry to focus on gender disparities in valvular heart disease in a real-world setting, aiming to fill a significant management gap that will help develop gender-specific, evidence-based guidelines for valvular heart disease.
Authors
- Pablo Pérez López (ORCID: https://orcid.org/0000-0003-4336-9425)
- Naeimeh Hosseini (ORCID: https://orcid.org/0000-0003-2308-1387)
- Alessia Gimelli (ORCID: https://orcid.org/0000-0003-3378-1723)
- Victoria Delgado (ORCID: https://orcid.org/0000-0002-9841-2737)
- Ali A Elzieny (ORCID: https://orcid.org/0000-0002-9533-3793)
- Julia Grapsa (ORCID: https://orcid.org/0000-0003-4620-6234)
- Ana G. Almeida (ORCID: https://orcid.org/0000-0003-0360-4363)
- Danilo Neglia (ORCID: https://orcid.org/0000-0003-0016-9538)
- Steffen Erhard Petersen (ORCID: https://orcid.org/0000-0003-4622-5160)
- Shehab Anwer (ORCID: https://orcid.org/0000-0003-4357-8913)
- Ana Teresa Timóteo (ORCID: https://orcid.org/0000-0001-6061-9663)
Institutions
- Boston University (US)
- Brigham and Women's Hospital (US)
- St Bartholomew's Hospital (GB)
- Harvard University (US)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Barts Health NHS Trust (GB)
- Hospital Universitario Puerta de Hierro Majadahonda (ES)
- Zurich Heart House (CH)
- Nova Medical (United States) (US)
- St. Thomas Hospital (CA)
- Magdi Yacoub Heart Foundation (EG)
- Hospital de Santa Marta (PT)
- Hospital de Santa Maria (PT)
- William Harvey Research Institute (GB)
- Hospital Universitari Germans Trias i Pujol (ES)
- Fondazione Toscana Gabriele Monasterio (IT)
- Universidad Autónoma de Madrid (ES)
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- European Heart Journal - Imaging Methods and Practice
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1093/ehjimp/qyaf123
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00