A Culture-Free Lipidomics-Based Screening Test for Uropathogens
The lysozyme-enhanced FLAT assay enables rapid and culture-free detection of both gram-negative and gram-positive uropathogens directly from urine. The unified workflow decreases the analytical turnaround time by at least 90% making it well-suited for high-throughput clinical laboratories.
Authors
- Pamela Kibsey
- Mert Pekcan (ORCID: https://orcid.org/0000-0003-3084-125X)
- David R. Goodlett (ORCID: https://orcid.org/0000-0002-8045-8200)
- Robert K. Ernst (ORCID: https://orcid.org/0000-0001-5016-8694)
- Michael X Chen
- Jun Liu (ORCID: https://orcid.org/0000-0002-1379-8512)
- Linda K. Nartey (ORCID: https://orcid.org/0000-0003-1402-4073)
- Victor Yuen
Institutions
- University of Maryland, Baltimore (US)
- Island Health (CA)
- University of British Columbia (CA)
- Ankara University (TR)
- University of Victoria (CA)
Publication Details
- Journal
- Clinical Chemistry
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1093/clinchem/hvaf164
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 0.00